Max Rempel, Ph.D.
San Diego, CA, USA · m: +1(585)705-1400 · linkedin.com/in/maxrempel
Ph.D. in Biology, 1994. Institute of Gene Biology, Moscow, Russia
M.S. in Chemistry, 1986. Lomonosov Moscow State University
Employment
2018–present: Founding CEO, DNA Resonance Research Foundation, San Diego, CA
2018–present: Chief Scientist, DNA Vibe, Centennial, CO
2023–2025: Director, Genomics and Microscopy Core, SCRM UCSD, San Diego, CA
2012–2018: Founding CEO, Localized Therapeutics, San Diego, CA
2006–2012: Research Faculty, Biology Department, University of Rochester, NY
2001–2002: Senior Scientist, Informax, Thermo Fisher Scientific, Bethesda, MD
1999–2006: Research Fellow, National Cancer Institute, NIH, Bethesda, MD
1996–1999: Postdoctoral Research Scientist, Medical College of Virginia, Richmond, VA
Funding
1R43MH110273-01A1 (SBIR), Myakishev-Rempel (PI), 2017–03/2019, NIH/NIMH: Optogenetic control over transgene expression for the therapy of brain and spine. Role: PI
1R43AR065884-01A1 (SBIR), Myakishev-Rempel (PI), 2015–2017, NIH/NIAMS: An infrared-activated promoter for gene therapy of arthritis. Role: PI
1R43AR057589 (SBIR), Myakishev-Rempel (PI), 2009–2011, NIH/NIAMS: Laser-guided gene therapy for cartilage defects. Role: PI
20000306 Myakishev-Rempel (PI), 2009, CEIS/NYSTAR: MRI imaging in light-activated gene therapy. Role: PI
5T32AR007472 Pentland (PI), 2006–2008, NIH/NIAMS: Training Grant in Dermatology. Role: Research Fellow
5R01MH045390 Straub (PI), 1996–1999, NIH/NIMH: Molecular Genetics of Schizophrenia. Role: Postdoc
5K05MH001277 Kendler (PI), 1996–1999, NIH/NIMH: Psychiatric Genetics. Role: Postdoc
5R01DA010228 Kendler (PI), 1996–1999, NIH/NIDA: Detecting Susceptibility Genes for Nicotine Addiction. Role: Postdoc
Publications
- Vikhorev AV, Rempel MM, Polesskaya OO, Savelev IV, Vetcher AA, Myakishev-Rempel MV. Patterns of transposable element distribution around chromatin ligation points revealed by Micro-C data analysis. Open Bioinformatics J. 2025;18.
- Savelev IV, Miller RA, Myakishev-Rempel M. (2025). Wie das Biofeld durch DNA-Resonanz erzeugt wird. In Rhythmische Vorteile in Big Data und Machine Learning (pp. 179–222).
- Myakishev-Rempel M, Savelev IV. (2025). Wie Schrödingers Mäuse Bewusstsein schaffen. In Rhythmische Vorteile in Big Data und Machine Learning (pp. 223–250).
- Vikhorev AV, Savelev IV, Polesskaya OO, Rempel MM, Miller RA, Vetcher AA, Myakishev-Rempel M. (2024). The Avoidance of Purine Stretches by Cancer Mutations. International Journal of Molecular Sciences, 25(20), 11050.
- Myakishev-Rempel M, Savelev I. (2022). Prediction of oscillation patterns of charges in a DNA sequence. US Patent Application 17/529,253.
- Myakishev-Rempel M, Savelev IV. (2022). How Schrödinger’s mice weave consciousness. In Rhythmic Advantages in Big Data and Machine Learning (pp. 201–224).
- Nygren J, Adelman RA, Myakishev-Rempel M, Sun G, Li J, Zhao Y. (2020). Centrosome as a micro-electronic generator in live cells. Biosystems, 197, 104210.
- Savelev I, Myakishev-Rempel M. 2020. Possible traces of resonance signaling in the genome. Progress in Biophysics and Molecular Biology, 151, pp.23–31.
- Savelev I, Myakishev-Rempel M. 2020. Evidence for DNA resonance signaling via longitudinal hydrogen bonds. Progress in Biophysics and Molecular Biology, 156, pp.14–19.
- Myakishev-Rempel M. The role of Alu-derived RNAs in Alzheimer’s and other neurodegenerative conditions. Med Hypotheses. 2018 Jun;115:29–34. PMID: 29685192
- Polesskaya O, Baranova A, Bui S, Kondratev N, Kananykhina E, Nazarenko O, Shapiro T, Nardia FB, Kornienko V, Chandhoke V, Stadler I, Lanzafame R, Myakishev-Rempel M. Optogenetic regulation of transcription. BMC Neurosci. 2018 Apr 19;19(1):12. PMID: 29745855
- Savelyev I, Zyryanova N, Polesskaya O, Anderson R, Tuszynski J, Myakishev-Rempel M. Microtubular Transmission in Millimeter Wave Therapy. Vixra, 1805.0104, 2018
- Myakishev-Rempel M, Stadler I, Polesskaya O, Motiwala AS, Nardia FB, Mintz B, Baranova A, Zavislan J, Lanzafame RJ. Red Light Modulates Ultraviolet-Induced Gene Expression in the Epidermis of Hairless Mice. Photomed Laser Surg. 2015 Oct;33(10):498–503. PMCID: PMC4605358
- Tian X, Azpurua J, Hine C, Vaidya A, Myakishev-Rempel M, Ablaeva J, Mao Z, Nevo E, Gorbunova V, Seluanov A. High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature. 2013 Jul 18;499(7458):346–349. PMCID: PMC3720720
- Myakishev-Rempel M, Stadler I, Brondon P, Axe DR, Friedman M, Nardia FB, Lanzafame R. A preliminary study of the safety of red light phototherapy of tissues harboring cancer. Photomed Laser Surg. 2012 Sep;30(9):551–558. PMCID: PMC3423866
- Myakishev-Rempel MM, Kuper J, Mintz B, Hutchinson S, Voris J, Zavislan K, Offley S, Nardia FB, Yaseen Z, Yen T, Zavislan JM, Maloney MD, Schwarz EM. Investigation of the peak action wavelength of light-activated gene transduction. Gene Ther. 2011 Nov;18(11):1043–1051. PMCID: PMC3530381
- Chatterjee R, Bhattacharya P, Gavrilova O, Glass K, Moitra J, Myakishev-Rempel M, Pack S, Jou W, Feigenbaum L, Eckhaus M, Vinson C. Suppression of the C/EBP family of transcription factors in adipose tissue causes lipodystrophy. J Mol Endocrinol. 2011.
- Myakishev-Rempel M, Polesskaya O, Kulichkova V, Baranova A, Gause L, Konstantinova I. PCR-based detection of Pol III-transcribed transposons and its application to the rodent model of ultraviolet response. Cell Stress Chaperones. 2008 Spring;13(1):111–6.
- Gerdes MJ, Myakishev-Rempel M, Frost NA, Rishi V, Moitra J, Glick A, Yuspa SH, Vinson C. Activator protein-1 activity regulates epithelial tumor cell identity. Cancer Res. 2006 Aug 1;66(15):7578–88.
- Paletzki R, Myakishev-Rempel M, Polesskaya O, Hyman S, Vinson C. Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization. Neuroscience. 2008 Apr 9;152(4):1040–53.
- Rozenberg JM, Shlyakhtenko A, Glass K, Rishi V, Myakishev-Rempel M, Fitzgerald PC, Vinson C. All and only CpG-containing sequences are enriched in promoters abundantly bound by RNA polymerase II in multiple tissues. BMC Genomics. 2008 Feb 5;9(1):67.
- Myakishev-Rempel M. Pipette device for efficient liquid handling. US Patent 10995634, 2005.
- Mir A, Myakishev-Rempel M, Polesskaya O, Moitra J, Petersen D, Miller L, Orosz A, Vinson C. A search for candidate genes for lipodystrophy, obesity, and diabetes via gene expression analysis of A-ZIP/F-1 mice. Genomics. 2003 Apr;81(4):378–90.
- Vinson C, Myakishev-Rempel M, Acharya A, Mir A, Moll J, Bonovich M. Classification of human B-ZIP proteins based on dimerization properties. Mol Cell Biol. 2002 Sep;22(18):6321–35. Review.
- Lueders K, Hu S, McHugh L, Myakishev-Rempel M, Sirota L, Hamer D. Genetic and functional analysis of single nucleotide polymorphisms in the beta2-neuronal nicotinic acetylcholine receptor gene (CHRNB2). Nicotine Tob Res. 2002 Feb;4(1):115–25.
- Straub R, MacLean C, Ma Y, Webb B, Myakishev-Rempel M, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, O’Neill F, Walsh D, Kendler K. Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes. Mol Psychiatry. 2002;7(6):542–59.
- Straub R, Jiang Y, MacLean C, Ma Y, Webb B, Myakishev-Rempel M, Harris-Kerr C, Wormley B, Sadek H, Kadambi B, Cesare A, Gibberman A, Wang X, O’Neill F, Walsh D, Kendler K. Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia. Am J Hum Genet. 2002 Aug;71(2):337–48.
- Myakishev-Rempel M, Khripin Y, Hu S, Hamer DH. High-throughput SNP genotyping by allele-specific PCR with universal energy-transfer-labeled primers. Genome Res. 2001 Jan;11(1):163–9.
- Sullivan P, Neale M, Silverman M, Harris-Kerr C, Myakishev-Rempel M, Wormley B, Webb B, Ma Y, Kendler K, Straub R. An association study of DRD5 with smoking initiation and progression to nicotine dependence. Am J Med Genet. 2001 Apr 8;105(3):259–65.
- Straub R, Sullivan P, Ma Y, Myakishev-Rempel M, Harris-Kerr C, Wormley B, Kadambi B, Sadek H, Silverman M, Webb B, Neale M, Bulik C, Joyce P, Kendler K. Susceptibility genes for nicotine dependence: a genome scan and follow-up in an independent sample suggests that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study. Mol Psychiatry. 1999 Mar;4(2):129–44.
- Straub R, MacLean C, Martin R, Ma Y, Myakishev-Rempel M, Harris-Kerr C, Webb B, O’Neill F, Walsh D, Kendler K. A schizophrenia locus may be located in region 10p15-p11. Am J Med Genet. 1998 Jul 10;81(4):296–301.
- Hawi Z, Myakishev-Rempel M, Straub R, O’Neill A, Kendler K, Walsh D, Gill M. No association or linkage between the 5-HT2a/T102C polymorphism and schizophrenia in Irish families. Am J Med Genet. 1997 Jul 25;74(4):370–3.
- Beritashvili D, Myakishev-Rempel M, Ershov G, Georgiev G, Kapanadze G. Centrifugal method and apparatus for isolating a substance from a mixture of substances in a sample liquid. US Patent 5,610,074, 1997.
- Myakishev-Rempel MV, Kapanadze GI, Shaikhayev GO, Malahova S, Georgiev GP, et al. (1995) Use of perchlorate precipitation to improve plasmid isolation. Moscow Institute of Gene Biology.
- Myakishev-Rempel MV, Kapanadze GI, Shaikhayev GO, Georgiev GP, Beritashvili DR. Extraction of DNA from the whole blood by silica gel. 1995. Institute of Gene Biology, Moscow.